Our science

    Publications
    • 01

      Effects of the novel compound DK223 on migration and proliferation of human keratinocytes and primary dermal fibroblasts,

      2014, International Journal of Molecular Sciences 15, 13091-13110
    • 02

      Soy isoflavone glicitin(4’-hydroxy-6-methoxyisoflavone-7-D-glucoside) promotes human dermal fibroblast cell proliferation and migration via TGF-β signaling,

      2015, Phytotherapy research, 29, 757-769
    • 03

      Dexamethasone inhibits TGF-β1-induced cell migration by regulating the ERK and AKT Pathways in Human Colon Cancer cells via Cyr61,

      2016, Cancer Res Treat. 48(3): 1141-1153
    • 04

      A novel synthetic material, BMM, accelerates wound repair by stimulating re-epithelialization and fibroblast activation,

      2018, Int J Mol Sci, 19(4), 1164
    • 05

      SIRT-1 regulates TGF-β-induced dermal fibroblast migration via modulation of Cyr61 expression,

      2018, Connective Tissue Research, 59:3, 245-254
    • 06

      TM4SF5-mediated CD44v8-10 splcing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis,

      2019, Cell Death & Disease, 10(9), 645
    • 07

      Cellular senescence and EMT crosstalk in bleomycin-induced pathogenesis of pulmonary fibrosis – an in vitro analysis,

      2019, Cell biology international,
    • 08

      Role of NAPDH oxidase and its therapeutic intervention in TGF-β-mediated EMT progression : an in vitro analysis on HeLa cervical cancer cells,

      2020, Applied Biological Chemistry, 63(1):1-8
    • 09

      Redox Regulation of NOX Isoforms on FAK(Y397)/SRC(Y416) Phosphorylation Driven Epithelial-to-Mesenchymal Transition in Malignant Cervical Epithelial Cells,

      2020, Cells 9(6)
    Patents
    No. Title of Patent Application/Registration Country Date Application No./Registration No.
    01

    Composition for Improving Pulmonary Fibrosis Using
    4',6,7-trimethoxyisoflavone and Catechol

    Registration Korea 17th, August, 2022 10-2292362
    Application PCT 6th, July, 2021 PCT/KR 2021/008552
    Application USA 19th, November, 2021 17/612,712
    02

    Composition for Improving Pulmonary Fibrosis Using
    4',6,7-trimethoxyisoflavone

    Application Korea 5th, July, 2021 10-2021-0087826
    03

    Composition for Improving Pulmonary Fibrosis Using
    Guaiacol and 4',6,7-trimethoxyisoflavone

    Application Korea 30th, December, 2021 10-2022-0137147
    Application PCT 29th, December, 2022 PCT/KR 2022/021678
    04

    Method for Screening Drug Candidates for Treating
    Pulmonary Fibrosis

    Application Korea 8th, February, 2022 10-2022-0016475