Our science

    논문
    • 01

      Effects of the novel compound DK223 on migration and proliferation of human keratinocytes and primary dermal fibroblasts,

      2014, International Journal of Molecular Sciences 15, 13091-13110
    • 02

      Soy isoflavone glicitin(4’-hydroxy-6-methoxyisoflavone-7-D-glucoside) promotes human dermal fibroblast cell proliferation and migration via TGF-β signaling,

      2015, Phytotherapy research, 29, 757-769
    • 03

      Dexamethasone inhibits TGF-β1-induced cell migration by regulating the ERK and AKT Pathways in Human Colon Cancer cells via Cyr61,

      2016, Cancer Res Treat. 48(3): 1141-1153
    • 04

      A novel synthetic material, BMM, accelerates wound repair by stimulating re-epithelialization and fibroblast activation,

      2018, Int J Mol Sci, 19(4), 1164
    • 05

      SIRT-1 regulates TGF-β-induced dermal fibroblast migration via modulation of Cyr61 expression,

      2018, Connective Tissue Research, 59:3, 245-254
    • 06

      TM4SF5-mediated CD44v8-10 splcing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis,

      2019, Cell Death & Disease, 10(9), 645
    • 07

      Cellular senescence and EMT crosstalk in bleomycin-induced pathogenesis of pulmonary fibrosis – an in vitro analysis,

      2019, Cell biology international,
    • 08

      Role of NAPDH oxidase and its therapeutic intervention in TGF-β-mediated EMT progression : an in vitro analysis on HeLa cervical cancer cells,

      2020, Applied Biological Chemistry, 63(1):1-8
    • 09

      Redox Regulation of NOX Isoforms on FAK(Y397)/SRC(Y416) Phosphorylation Driven Epithelial-to-Mesenchymal Transition in Malignant Cervical Epithelial Cells,

      2020, Cells 9(6)
    특허현황
    No. 특허의 내용 출원/등록 국가명 출원/등록일 출원번호/등록번호
    01 트리메톡시 이소플라본과 카테콜을 이용한 폐섬유화증 개선용 조성물 등록 대한민국 2021. 08. 17 제 10-2292362호
    출원 PCT 2021. 07. 06 PCT/KR 2021/008552
    출원 미국 2021. 11. 19 17/612,712
    02 트리메톡시 이소플라본을 이용한 폐섬유화증 개선용 조성물 출원 대한민국 2021. 07. 05 10-2021-0087826
    03 트리메톡시 이소플라본 또는 구아이아콜을 이용한 폐섬유화증 개선용 조성물 출원 대한민국 2021. 12. 30 10-2022-0137147
    출원 PCT 2022. 12. 29 PCT/KR 2022/021678
    04 폐섬유화증 치료를 위한 후보약물의 스크리닝 방법 출원 대한민국 2022. 02. 08 10-2022-0016475