논문
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01
Effects of the novel compound DK223 on migration and proliferation of human keratinocytes and primary dermal fibroblasts,
2014, International Journal of Molecular Sciences 15, 13091-13110 -
02
Soy isoflavone glicitin(4’-hydroxy-6-methoxyisoflavone-7-D-glucoside) promotes human dermal fibroblast cell proliferation and migration via TGF-β signaling,
2015, Phytotherapy research, 29, 757-769 -
03
Dexamethasone inhibits TGF-β1-induced cell migration by regulating the ERK and AKT Pathways in Human Colon Cancer cells via Cyr61,
2016, Cancer Res Treat. 48(3): 1141-1153 -
04
A novel synthetic material, BMM, accelerates wound repair by stimulating re-epithelialization and fibroblast activation,
2018, Int J Mol Sci, 19(4), 1164 -
05
SIRT-1 regulates TGF-β-induced dermal fibroblast migration via modulation of Cyr61 expression,
2018, Connective Tissue Research, 59:3, 245-254 -
06
TM4SF5-mediated CD44v8-10 splcing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis,
2019, Cell Death & Disease, 10(9), 645 -
07
Cellular senescence and EMT crosstalk in bleomycin-induced pathogenesis of pulmonary fibrosis – an in vitro analysis,
2019, Cell biology international, -
08
Role of NAPDH oxidase and its therapeutic intervention in TGF-β-mediated EMT progression : an in vitro analysis on HeLa cervical cancer cells,
2020, Applied Biological Chemistry, 63(1):1-8 -
09
Redox Regulation of NOX Isoforms on FAK(Y397)/SRC(Y416) Phosphorylation Driven Epithelial-to-Mesenchymal Transition in Malignant Cervical Epithelial Cells,
2020, Cells 9(6)
특허현황
No. | 특허의 내용 | 출원/등록 | 국가명 | 출원/등록일 | 출원번호/등록번호 |
01 | 트리메톡시 이소플라본과 카테콜을 이용한 폐섬유화증 개선용 조성물 | 등록 | 대한민국 | 2021. 08. 17 | 제 10-2292362호 |
출원 | PCT | 2021. 07. 06 | PCT/KR 2021/008552 | ||
출원 | 미국 | 2021. 11. 19 | 17/612,712 | ||
02 | 트리메톡시 이소플라본을 이용한 폐섬유화증 개선용 조성물 | 출원 | 대한민국 | 2021. 07. 05 | 10-2021-0087826 |
03 | 트리메톡시 이소플라본 또는 구아이아콜을 이용한 폐섬유화증 개선용 조성물 | 출원 | 대한민국 | 2021. 12. 30 | 10-2022-0137147 |
출원 | PCT | 2022. 12. 29 | PCT/KR 2022/021678 | ||
04 | 폐섬유화증 치료를 위한 후보약물의 스크리닝 방법 | 출원 | 대한민국 | 2022. 02. 08 | 10-2022-0016475 |